HeyJaredSøren Hough
- Indexed articles, last 90 days
- 7
- Latest publication
- Oct 1, 2026
- Outlet visibility, for SCM
- Top 10M sites
- Earliest in this view
- Jul 7, 2026
Latest articles
In vivo CRISPR treatment for HAE receives BLA approval (opens the original)
Read excerpt
The one-dose genome editing therapy would transform the treatment landscape for patients dealing with a life-threatening and unpredictable disease. On a Dose of Discovery episode earlier this year, CRISPR trailblazer and Intellia Therapeutics co-founder Erik Sontheimer referred to lonvoguran ziclumeran (lonvo-z) as “the Intellia drug that is likely to get approved before too long.” It turns out he was right; the US Food and Drug Administration (FDA) approved the company’s biologics license appli
Anne Conibear on how small changes reshape peptide biology (opens the original)
Read excerpt
How toxic cone snails and a "combination of synthesis and structure" led one scientist into the world of peptide research. What can cone snail venom teach us about peptides and new medicines? In this episode of Dose of Discovery, Anne Conibear joins Søren and AJ to explain how small chemical changes can affect protein and peptide behavior in the cell. A lockdown project investigating cone snail venom gave Anne the opportunity to explore how these slow-moving predators use potent peptide toxins t
Getting siRNAs into the brain without transferrin receptors (opens the original)
Read excerpt
Manifold Bio uses AI to find novel “portals” for getting antibodies and oligos past the blood-brain barrier. fThe blood-brain barrier (BBB) is excellent at keeping foreign material – including therapeutics – out of the central nervous system (CNS). That’s a particular problem for treating multiple forms of neurodegeneration, which requires engaging with the disease directly in the brain. The most popular option for getting around the BBB is by conjugating the therapeutic to a transferrin recepto
RNA and ethical quandaries in Spider-Man: Brand New Day (opens the original)
Read excerpt
Marvel’s latest web-crawling adventure features a surprising dive into cutting-edge medicine, providing an opportunity for effective science communication. Note that this article contains minor spoilers for Brand New Day. No, that doesn’t include Sadie Sink’s mystery role. I sat down at the movie theater to watch Spider-Man: Brand New Day with my mind empty. I fully intended to unwind from a day of thinking about science with some big-screen comic book fun. This was superhero escapism distilled,
Erik Sontheimer on the evolution of genome editing (Podcast) (opens the original)
Read excerpt
How the dawn of CRISPR research led to a therapeutic revolution. CRISPR pioneer Erik Sontheimer joins hosts Søren and AJ to discuss how curiosity-driven research revealed a powerful genome editing technology. This episode of Dose of Discovery looks at the landmark research that revealed how CRISPR could target DNA and the scientific discoveries that have turned it into a revolutionary research tool. Erik looks back at the “Wild West” years of early CRISPR research, the unexpected discoveries tha
Publishing over time
Last 90 days. Choose a month to open its work.
Recurring subjects
Named in the text we hold. One piece can cover several.
Audience
Top 10M sites
For SCM, the outlet · Measured Aug 1, 2026
Website popularity band, not a count of readers or article views.
About this data
Counts cover the work we have indexed. Tone needs enough text and a confident classification. Excerpts and episode notes are not full articles or transcripts.
Identity or attribution wrong? Suggest a correction.