HeyJaredPeter Simons
- Indexed articles, last 90 days
- 1
- Latest publication
- Jul 9, 2026
- Outlet visibility, for Mad In America
- Top 5M sites
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- Jul 9, 2026
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Depression Drug Approved by FDA Had 11 Failed Trials and an Advisory Committee Vote Against Approval (opens the original)
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Editor’s Note: This piece originally appeared on the Mad in America Substack. Two positive studies out of 13 conducted. Rejected by the FDA four times. An FDA advisory committee vote against approval. Yet in 2023, gepirone (Exxua) was approved for treating depression. As of December 2025, it’s now commercially available. How does this keep happening? How can the FDA leaders keep approving drugs against the advice of its scientific advisory boards (see the aducanumab controversy)? How can they ke
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