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Lancet Rheumatol

Reporter · US

Indexed articles, last 90 days
4
Latest publication
Sep 28, 2026
Outlet visibility, for Medscape
Top 50K sites
Earliest in this view
Aug 27, 2026

Latest articles

  1. Article · Sep 28, 2026 · Lancet Rheumatol. 2026;

    Is Rozanolixizumab Effective in Severe Fibromyalgia? (opens the original)

    Excerpt · English

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    Rozanolixizumab, an antibody targeting the neonatal Fc receptor for immunoglobulin G (IgG), showed modest improvement in pain interference and fibromyalgia impact among patients with severe fibromyalgia but did not significantly reduce pain intensity or fatigue. The primary endpoint met the prespecified one-sided statistical threshold but not the standard two-sided significance level. "The small sample size and marked heterogeneity in patient responses limit interpretability of findings. Further

  2. Article · Sep 1, 2026 · Lancet Rheumatol. 2026-08-27;

    B-Cell Depletion Tied to Rituximab Response in Myopathies (opens the original)

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    Complete depletion of memory B cells and plasmablasts within 2 weeks of rituximab infusion was associated with clinical response in patients with idiopathic inflammatory myopathies (IIM), and highly sensitive flow cytometry (HSFC) detected these differences, while conventional flow cytometry did not. "Although these findings require prospective validation, combining HSFC-defined minimal residual disease assessment with autoantibody profiling could help to uncover the pathogenic B-lineage program

  3. Article · Aug 31, 2026 · Lancet Rheumatol. 2025;7(9):e642-e651.

    Does Tapering TNF Inhibitors Maintain Low Disease Activity? (opens the original)

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    A treat-to-target tapering strategy for TNF inhibitors appeared to maintain low disease activity for up to 2 years in patients with psoriatic arthritis and axial spondyloarthritis. "[T]hese data indicate that a taper-to-target strategy is effective and leads to substantial TNF inhibitor dose reduction, but optimal execution of such a strategy in routine care is more challenging than in the context of a clinical trial," the authors of the study wrote. The study was led by Amy C.D. Peeters, MD, Si

  4. Article · Aug 27, 2026 · Lancet Rheumatol. 2026;

    Early Screening Linked to Better Outcomes in RA (opens the original)

    Excerpt · Positive tone · English

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    Patients with rheumatoid arthritis (RA) referred through an early arthritis recognition clinic experienced significantly less functional disability and had more than twice the likelihood of sustained disease-modifying antirheumatic drug (DMARD)-free remission over 5 years compared with those referred through regular pathways. "The [study] results, therefore, have great added value because they indicate that an active intervention leading to an earlier diagnosis of rheumatoid arthritis, in combin

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