HeyJaredJAMA Ophthalmol
- Indexed articles, last 90 days
- 5
- Latest publication
- Sep 25, 2026
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- Aug 17, 2026
Latest articles
PCV: Retina Scans May Guide Who Needs Ongoing Eye Injections (opens the original)
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Among eyes with polypoidal choroidal vasculopathy (PCV) — a subtype of age-related macular degeneration — that achieved complete regression after receiving either three or six monthly injections of aflibercept, half stayed fluid-free for up to 2 years with an as-needed treatment approach, while the other half experienced recurrence. Eyes with substantial bleeding under the retina at baseline were less likely to have recurrence, while those with a larger residual "double-layer sign" on retinal im
Modified Vitamin A May Slow Rare Vision Disease (opens the original)
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A new clinical trial found that a deuterium-modified form of vitamin A — which replaces most of the body's natural vitamin A and stops it from clumping — slowed the growth of retina-damaging lesions by more than 20% in patients with Stargardt disease, with no serious safety concerns over 2 years. "Slowing the progression of a once-inexorable, vision-impairing disease is a worthwhile pursuit with potential to address an unmet medical need," experts wrote in an accompanying editorial. "In the real
Letter-Matching Test Favored for Vision Screening in Kids (opens the original)
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In young children, the HOTV letter-matching vision test was associated with slightly better measurements of uncorrected visual acuity (UCVA) and was linked to fewer referrals for reduced vision than the tumbling E test. "[The authors] have provided a robust analysis comparing the HOTV test to the tumbling E test, concluding that the HOTV test is superior in multiple measures and therefore recommend its use in screening," Anna R. O'Connor, PhD, wrote in an invited commentary accompanying the jour
Aspherical Lenslets Slow Myopia Progression in Kids (opens the original)
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Spectacle lenses with highly aspherical lenslets (HAL) reduced myopia progression by more than 70% and axial elongation by more than 50% compared with single-vision lenses (SVL) in children aged 6 to 12 years over 24 months. "Given the diversity of the participants recruited across 9 US investigational sites, these findings are likely generalizable to the broader population of North American children seeking myopia management in clinical practice," the authors wrote. “Longer follow-up is needed
Pachychoroid Disease Progression Remains Low (opens the original)
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Eyes with pachychoroid disease subtypes remained largely stable over 2 years, with progression to a worse subtype occurring in only 7.3% of cases. Neovascularization developed in 3.4% of eyes, and all cases exhibited shallow, irregular retinal pigment epithelium (RPE) elevation at baseline — a potential imaging marker for identifying higher-risk eyes. "Taken together, within a relatively small cohort, findings suggest eyes with pachychoroid subtype typically are stable over 2 years, although a s
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