HeyJaredAlzheimers Dement
- Indexed articles, last 90 days
- 4
- Latest publication
- Aug 11, 2026
- Outlet visibility, for Medscape
- Top 50K sites
- Earliest in this view
- Aug 4, 2026
Latest articles
Plasma p-Tau217 Drop Tied to Better Outcomes on Lecanemab (opens the original)
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Plasma phosphorylated tau 217 (p-tau217) levels decreased within 3 months of lecanemab initiation in patients with Alzheimer's disease (AD), with a more pronounced decline occurring between 3 and 6 months. Patients who experienced greater reductions in p-tau217 showed more favorable cognitive trajectories. "Early changes in plasma p-tau217 may help identify responders and non-responders, enabling more individualized treatment strategies," the authors of the study wrote. "These findings support t
Cardiac Output Tied to Brain Volume in APOE-ε4 Carriers (opens the original)
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Lower cardiac output was associated with a smaller brain volume in older adults carrying the apolipoprotein E (APOE)-ε4 allele, but not in non-carriers, a study found. "Lower cardiac output at baseline is associated with small brain volumes over time in the medial temporal lobes in participants who are APOE-ε4 carriers. Results suggest that subclinical cardiac dysfunction may be a key risk factor for future neurodegeneration in individuals with a genetic predisposition to Alzheimer’s disease," t
Hypertension, Heart Disease Affect Brain's White Matter (opens the original)
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Hypertension and heart disease are linked to widespread damage in the brain's white matter, according to a new study of older adults, which found altered microstructure across 48 distinct brain tracts. The findings point to tighter management of both conditions as a way to help protect brain health. "Among VRFs, hypertension and heart disease explain the greatest unique variance in white matter microstructure,” the authors of the study wrote. “This study indicates that prioritizing interventions
BP Variability Tied to Cognitive Decline (opens the original)
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Higher visit-to-visit systolic blood pressure (BP) variability was independently associated with faster cognitive decline in adults at elevated cardiovascular risk, regardless of mean BP levels in a study. "These findings identify BPV as a potential vascular contributor to cerebral end-organ injury beyond conventional BP control," the authors of the study wrote. The study was led by Yue Qiao, Department of Neurology, Xuanwu Hospital Capital Medical University, National Centre for Neurological Di
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Top 50K sites
For Medscape, the outlet · Measured Aug 1, 2026
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