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What's it Worth? A Journal Club Podcast

Get into the weeds with us as we take deep dives into clinical trials and build the essential skills of evidence critique!

Podcast · By Diana Langworthy · English · Official site

Indexed episodes, last 90 days
6
Latest publication
Aug 11, 2026
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Earliest in this view
Jul 14, 2026
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Latest episodes

  1. Episode · Aug 11, 2026

    S4E10 - Watchman Vs. DOACs for Prevention of Stroke & Systemic Embolism (opens the original)

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    Stroke prevention in atrial fibrillation is always a balancing act: reduce clot risk without causing unacceptable bleeding. For years, oral anticoagulants have been the cornerstone of that decision. But what happens when a device enters the conversation? In this episode, host Dr. Diana Langworthy is joined by Dr. Jen Osborn , cardiology clinical pharmacy specialist at UMMC East Bank Hospital and residency program director for the PGY2 Thrombosis and Hemostasis Management Residency. Together, the

  2. Episode · Jul 28, 2026

    S4E9.5 - What's it Worth? For Everyone. Can Lavender Oil Help Anxiety? What to Know About Silexan (opens the original)

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    In this What's It Worth? For Everyone episode, we're asking: Can lavender oil help with anxiety? If you've ever felt anxious before a big test, job interview, medical appointment, or major life event, you're not alone. But when is anxiety a normal response to stress — and when is it something more, like generalized anxiety disorder? In this episode, we talk about the difference between short-term situational anxiety and ongoing anxiety symptoms that may need support from a healthcare professiona

  3. Episode · Jul 28, 2026

    S4E9 - Anxiety Treatment Rankings: What a Network Meta-Analysis Can and Can't Tell Us (opens the original)

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    Welcome back to What's it Worth? In this episode, we tackle treatment options for a common mental health concern - anxiety. Your host, Dr. Diana Langworthy, is joined by Dr. Lucas Kosobuski , an inpatient pharmacist at St. Luke's in Duluth with prior experience providing ambulatory care services in an inpatient substance use treatment program. Together, they decode a 2025 systematic review and network meta-analysis comparing medications for anxiety disorders, including Silexan , a proprietary or

  4. Episode · Jul 21, 2026

    S4E8 - Is it Possible to Decouple Bleeding from Clotting? Insights from the AZALEA-TIMI 71 Trial (Factor XI Series Part 2 of 2) (opens the original)

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    In Part 2 of our back-to-back series on the novel frontier of Factor XI inhibition, host Dr. Diana Langworthy and student co-hosts Caleb Nelson-Lange and Tim Haas dive into the AZALEA-TIMI 71 trial. Following our Part 1 discussion on the early termination of the OCEANIC-AF trial (asundexian), we turn our attention to abelacimab —a high-affinity, fully human monoclonal antibody that targets Factor XI. Unlike the small-molecule asundexian, abelacimab offers a unique pharmacokinetic profile with a

  5. Episode · Jul 14, 2026

    S4E8.5 - What's it Worth? For Everyone. Are We Waiting Too Long for New Treatments? (opens the original)

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    In this What's It Worth? For Everyone episode, we're asking: Are we waiting too long for new treatments? If you've ever heard about a promising new medication, peptide, or breakthrough therapy and wondered, "If it works so well, why isn't everyone using it yet?" —you're not alone. It can feel frustrating to hear about exciting discoveries while waiting years before they become part of routine healthcare. In this episode, we take you behind the scenes of the scientific process to explore what hap

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