Trying To Be Positive With Anne Matthews
Trying to Be Positive is the hand that you've been wanting to hold on your fertility journey. Anne Matthews is a passionate advocate for reproductive health and normalizing the conversation around fertility, labour, loss and menstruation.
- Indexed episodes, last 90 days
- 3
- Latest publication
- Sep 22, 2026
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- Earliest in this view
- Aug 25, 2026
Latest episodes
A Fertility Story - Multiple Losses, Failed Transfers & Natural Conception at 44 (opens the original)
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Anne is back with Hayley, sharing her fertility journey from egg freezing at 34 through pregnancy at 44. She froze her eggs at 34, did a second retrieval at 38 that included making two embryos with a sperm donor before she'd even met her husband, and went on to have two unplanned chemical pregnancies with her now-husband before they'd officially started trying. She shares the loss of a pregnancy after IUI at 9 to 10 weeks, later confirmed to have an extra chromosome, and how three euploid embryo
A Fertility Story - Six Pregnancy Losses, IVF & DNA Fragmentation (opens the original)
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Anne is back with Leslie Fair, sharing three and a half years of trying to build a family that included six pregnancy losses, the pressure of being told her age was the problem despite bloodwork that looked completely normal, and two rounds of IVF. She walks through the devastating moment a technician told her "it happened again" during an ultrasound with no support offered afterward, why she and her husband kept trying to collect more embryos even when it wasn't working, and how a comment from
Sperm DNA Fragmentation & Male Fertility: New Research on Egg Repair, Varicoceles & Paternal Age (opens the original)
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Anne is back solo, breaking down the latest research on sperm biology and why the old "sperm just delivers DNA" model is outdated. She covers a 2025 study from the Wellcome Sanger Institute and Harvard Medical School on "selfish sperm selection," where certain mutations allow sperm-producing stem cells to outcompete healthy ones as men age. She explains new research on imprint control regions and paternal age, and reframes what "egg quality" actually means: the egg's job isn't just to accept spe
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