HeyJaredThrombo Trial Files
Free bimonthly newsletter that summarizes the most significant, practice-changing hematology randomized controlled trials, straight to your inbox.
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- Aug 13, 2026
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- Aug 13, 2026
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Thrombo Trial Files: YEARS Algorithm in Cancer, Intermediate-Dose Heparin in COVID-19, and ASA for VTE Prevention Post TKA (opens the original)
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YEARS Algorithm for Diagnosis of Suspected Pulmonary Embolism in Patients With CancerAkerboom B et al. JAMA (July 2026)Bottom Line: The Hydra study was an open-label, randomized, noninferiority trial conducted from August 22, 2019, to August 21, 2025, involving 698 patients with active cancer and suspected acute pulmonary embolism (PE). Participants were randomly assigned to receive diagnostic management by the YEARS algorithm or CTPA only. The primary outcome was symptomatic venous thromboembol
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