HeyJaredThis Week In Medicine
Welcome to This Week in Medicine - Your Filtered Medical Journal SummaryLooking to stay up-to-date with the latest medical research but short on time?
- Indexed episodes, last 90 days
- 32
- Latest publication
- Sep 1, 2026
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- Earliest in this view
- Jul 8, 2026
Latest episodes
Circulation 8 2026 Bempedoic Acid and First and Recurrent Limb Outcomes in Statin-Intolerant Patients With Peripheral Artery Disease (opens the original)
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This research study investigates whether bempedoic acid can effectively protect patients with peripheral artery disease (PAD) from severe leg-related complications. By analyzing data from a large clinical trial of individuals who could not tolerate statins, researchers discovered that this medication significantly decreased the risk of both initial and repeat limb events, such as emergency surgeries or severe blockages. The findings emphasize that managing cholesterol is vital for preventing maj
Circulation 8 2026 Semaglutide and the Inflammatory Pathways to Cardiovascular Health (opens the original)
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This study explores how the medication semaglutide reduces the risk of major heart-related events by targeting chronic inflammation in patients with cardiovascular disease. Researchers tracked a specific protein marker, hsCRP, and discovered that lowering this indicator significantly improved patient survival regardless of initial weight or cholesterol levels. Crucially, the drug’s ability to dampen the inflammatory responsehappened rapidly and functioned independently of weight loss, suggesting
JAMA August 2026 Methadone vs Buprenorphine-Naloxone in Opioid Overdose Survivors (opens the original)
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This study evaluates whether methadone or buprenorphine-naloxone is more effective at preventing mortality among high-risk individuals who have recently survived an opioid overdose. By tracking thousands of patients in Ontario over a several-year period, researchers discovered that those who began a methadone regimen experienced a lower risk of death within the first year compared to those prescribed the alternative. A key factor in this outcome appeared to be treatment retention, as patients st
JAMA August 2026 Arginine Therapy for Sickle Cell Disease Acute Pain Episodes (opens the original)
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This clinical trial investigated whether administering intravenous arginine could effectively alleviate the intense pain crises commonly experienced by young patients with sickle cell disease. Although previous smaller studies suggested that this amino acid might reduce hospital stays and the need for heavy narcotics, this rigorous phase 3 study was halted early for futility after finding no significant benefits. The researchers discovered that arginine was no more effective than a placebo in sh
JAMA August 2026 Predictive Utility of Coronary Artery Calcium Score Added to the PREVENT Atherosclerotic Cardiovascular Disease Equations (opens the original)
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This study examines whether measuring coronary artery calcium (CAC)—a marker of plaque buildup—improves the accuracy of a new medical tool called the PREVENT equations for predicting heart disease risk. Researchers analyzed data from over 6,000 adults to see if adding these heart scans to standard risk assessments helped doctors better categorize patients' 10-year chances of suffering a cardiovascular event. While the results showed only a modest improvementin overall predictive power, the data
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