HeyJaredThe Science of Age-less Living
Welcome to The Science of Age-Less Living! Dr. Ethan Hausman-Marquis—logevity researcher, biohacker and founder of The Catalyst Clinic—shares his journey into the fields of aesthetics, regenerative medicine, and longevity science, and offers a look at what the future of…
- Indexed episodes, last 90 days
- 8
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- Sep 3, 2026
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- Jul 7, 2026
Latest episodes
Age-less in Japan: What the Longevity Data Actually Shows (opens the original)
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This episode of The Science of Age-less Living was recorded on location in Japan and tackles one of the most repeated — and least fact-checked — claims in the longevity space: that Okinawa holds the secret to extreme human lifespan. Rather than repeating the usual Blue Zone narrative, the episode opens by confronting a documented problem with the underlying data, including Japan's mid-2000s centenarian record scandal, before asking a more rigorous question: what does Japan's national, verifiable
Age-less by Design: The Centenarian Genes That Rewrite How We Grow Old (opens the original)
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What separates someone managing a pharmacy's worth of medications at seventy-five from someone who's just getting started on the road to a hundred and two? In this episode, we crack open the biological instruction manual of the world's centenarians and read its most remarkable pages. We start with a crucial distinction — the difference between lifespan (how long you live) and healthspan (how long you live well ) — and the striking pattern researchers call the compression of morbidity: the way th
The Age-less Night: How Your Pineal Gland Rewrites Your Genes While You Sleep (opens the original)
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Most people treat sleep as simple recovery, but this episode reframes it as the nightly window in which a gland smaller than a pea helps decide how fast you age. That gland is the pineal gland, buried at the center of your brain, and its job is to release melatonin — not really a "sleep chemical" but a darkness signal that tells every cell in your body it's night. This signal is wired to light hitting your eyes and routed through your brain's master clock, the SCN. The catch: the pineal gland te
The Age-Less Off-Ramp: What Happens When You Stop GLP-1s (opens the original)
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The GLP-1 receptor agonists are the most effective weight loss agents ever brought to market, and their efficacy is entirely contingent on continued administration. Three randomized withdrawal studies across two molecules make this unambiguous: the STEP-1 extension found participants regained roughly two-thirds of their lost weight within a year of stopping, with blood pressure, lipids, glycaemia and inflammatory markers reverting alongside it. STEP-4 and SURMOUNT-4 showed the same pattern under
Age-less or Overhyped? The Sixty-Year Cerebrolysin Puzzle | The Age-Less Top 20 Peptides (opens the original)
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Episode summary Cerebrolysin is a peptide preparation with a strange résumé: developed in Austria more than sixty years ago, approved in nearly fifty countries for stroke, traumatic brain injury, and dementia, put through hundreds of clinical trials — and yet still surrounded by a genuinely unresolved question about whether it works. In this episode we unpack what it actually is (not a single peptide, but a standardized mixture of amino acids and small fragments made by enzymatically digesting p
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