The ReProgram
The ReProgram is dedicated to exploring how we can extend the healthy human lifespan through science and self-understanding. Hosted by Dr.
- Indexed episodes, last 90 days
- 9
- Latest publication
- Sep 7, 2026
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- Earliest in this view
- Jul 6, 2026
Latest episodes
The Hidden Dangers of Aging Blood: What You Need to Know (opens the original)
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ReProgram Episode 25: 🩸 YOUR BLOOD MAY BE AGING BEFORE YOU ARE 🧠 Episode Overview Blood aging is often overlooked, but the hematopoietic stem cells inside your bone marrow carry a decades-long history.Your blood is not just a fluid; it is a continuously renewing organ system. As the stem cells that manufacture your blood cells age, they can shift immune composition and increase susceptibility to inflammation. This process is central to understanding how systemic aging actually unfolds, moving be
Start Here: The ReProgram | Longevity Science Without the Hype (opens the original)
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Welcome to The ReProgram. Longevity science moves a lot slower than longevity marketing.The ReProgram explores the biology of aging, longevity drugs, regenerative medicine, nutrition, exercise, biotechnology, and the emerging science that may help us live longer, healthier lives. Mechanism over marketing. Evidence over anecdotes. Trade-offs over hype.Understand Aging. Build Resilience. Extend Healthspan.
Can We Reprogram Aging? Epigenetics, Cell Identity & the Future of Rejuvenation | Dr. Jose Polo (opens the original)
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🎬 EPISODE OVERVIEW Every cell in your body contains essentially the same DNA, yet a neuron behaves nothing like a skin cell. So what actually gives a cell its identity — and how permanent is that identity?In this episode, Dr. George Murphy sits down with epigenetics and cellular reprogramming expert Dr. Jose Polo to explore how cells establish identity, how that identity can be rewritten, and what reprogramming really means for aging and rejuvenation.They discuss why cellular reprogramming is no
Creatine for Longevity? What the Science Actually Shows (opens the original)
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🧠 EPISODE OVERVIEW Creatine is cheap, widely available, and backed by an unusually large body of human research. But its biology extends well beyond the gym. The creatine–phosphocreatine system helps cells rapidly regenerate ATP when energy demand rises—in both muscle and brain. In this episode, we examine the evidence for creatine and muscle preservation, cognition and brain resilience, kidney safety, dosing, and emerging high-dose brain protocols. And most importantly: does any of this make cr
Can We Make Our Pets Live Longer? The Science of Pet Longevity (opens the original)
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🐾 EPISODE OVERVIEW This episode asks a deceptively simple question: Can we actually help our dogs and cats live longer, healthier lives?We explore why companion animals are unusually powerful models of aging, why “one dog year equals seven human years” is biologically wrong, what the Dog Aging Project is revealing, what pet owners can reasonably do today, and where emerging interventions like rapamycin, canine longevity drugs, AIM therapy, and gene therapy fit into the evidence. 🔑 KEYWORDS Pet l
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