Tacos and Tech Podcast
The Tacos and Tech Podcast highlights the builders of companies, technologies, ecosystems with a local flair for our lifestyle as well. risingtidepartners.substack.com
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- Indexed episodes, last 90 days
- 6
- Latest publication
- Sep 22, 2026
- Audience
- Checking…
- Earliest in this view
- Jul 8, 2026
Latest episodes
Thirst Is a Lagging Indicator (opens the original)
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Dr. Debbie Chen found the water signal in her own PhD data around 2007, laughed it off, and did nothing with it for a decade. Then came years of amateur Muay Thai and cramping through every session, then a dehydration health scare of her own. She’s now founder and CEO of Hydrostasis, maker of the GECA Watch, which has sold out twice. She and Neal get into why thirst is a lagging indicator, why she believes hydration is the only truly actionable thing a wrist device can measure, the multi-pivot r
Signals Before Symptoms (opens the original)
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Neal sits down with Adam Jacobs, President of Xzōm, a San Diego company developing a near-patient platform for isolating and analyzing exosomes from a small blood sample in under 30 minutes. Exosomes are tiny particles released by living cells that carry proteins and genetic material. Researchers believe these particles could provide useful signals about disease earlier or more dynamically than some existing biomarkers. Xzōm is working to turn that science into a compact testing platform, using
The Connective Tissue (opens the original)
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Neal sits down with Eric Weiss, a fellow longtime builder in San Diego’s startup ecosystem. Eric is a self-described “parallel entrepreneur,” founder coach, President of the Design Forward Alliance - which produces San Diego Design Week—and Vice Chair of Startup San Diego. Neal and Eric first crossed paths during the early days of San Diego’s startup community, around EvoNexus and the 101 Broadway vertical campus that helped give rise to Startup Week and Startup San Diego. They revisit that era
Beyond the Blueprint (opens the original)
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Episode Summary Neal sits down with Janine McMurdie, Chief Commercial Officer of Pictor, a proteomics platform company that expanded from New Zealand to Carlsbad. Janine explains why your DNA is only the blueprint - and why proteins, which change in real time as your body responds to a drug or an infection, tell the fuller story. They get into Pictor’s partner-driven, capital-efficient model, how the platform runs a complex panel of biomarkers as a single answer (for everything from cattle herds
Why Great Companies Go Bad (opens the original)
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Episode Summary Recorded live at the San Diego Angel Conference finale at SDSU, Eric Ries — author of The Lean Startup — sits down with product leader and founder coach Vidya Dinamani to unpack his new book, Incorruptible. His argument: there’s a gravitational force that pulls even mission-driven companies toward decay — “the making of money without the creating of value” — and the more successful you get, the bigger a target you become. Eric walks through how it happens (stack-ranking by ROI, t
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