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Sequence Space

Reflections on science, democracy, and the future, written by a biotech scientist, R&D executive, and consultant. Often distracted by current events. Opinions mine. 🇨🇦🇺🇸

Newsletter · By Simon Delagrave, PhD · Official site

Indexed issues, last 90 days
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Sep 27, 2026
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Latest issues

  1. Issue · Sep 27, 2026

    I was assaulted with a paperclip (opens the original)

    Excerpt · Critical tone

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    In 2024, I cofounded a biotech company that focused on using protein design to make new molecular tools for R&D. Grounded in machine learning, the technology underlying this business had only been described in the scientific literature a few months earlier. Given this novelty, it probably shouldn’t be surprising that we got a lot of different questions about the technology and its applications. The questions came from potential investors, customers, friends, and hapless people we met at cocktail

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