HeyJaredSELF Principle with Dr. Sean
Welcome to the SELF Principle Podcast with Dr. Sean Hashmi—a board-certified nephrologist and obesity medicine specialist helping you live longer through evidence-based medicine.SELF stands for Sleep, Exercise, Love, and Food—the four pillars of lasting health.Each episode…
- Indexed episodes, last 90 days
- 9
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- Aug 2, 2026
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- Jul 5, 2026
Latest episodes
Dialysis Timing: What Actually Decides When You Start (opens the original)
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Three people can have the exact same kidney number, and completely different futures. One needs dialysis this year. One never will. Nephrologist Dr. Sean Hashmi breaks down the biggest myth in kidney care: that a single eGFR number decides when you need dialysis. There is no eGFR threshold that automatically triggers dialysis, according to a 2024 review in JAMA. What actually decides timing is a combination of symptoms, fluid status, blood acid level, and potassium, not a single lab value. Dr. H
This Sign Means Your Kidneys Are Already Damaged (opens the original)
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Your kidneys can lose more than half their function and never once make you feel sick. Nephrologist Dr. Sean Hashmi walks through the real warning signs of kidney disease, including the ones almost everyone misses because they blame them on something else. Fewer than one in 20 people with early kidney disease are aware they have it, because kidneys are built with so much spare filtering capacity that blood tests can look normal while damage quietly continues underneath. Dr. Hashmi covers the eig
Do Proton Pump Inhibitors Cause Kidney Disease? (opens the original)
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Do heartburn pills like omeprazole really damage your kidneys? Nephrologist Dr. Sean Hashmi breaks down what the actual research found, how big the risk really is, and who carries it versus who barely does. Large observational studies do show a higher rate of chronic kidney disease in people who take proton pump inhibitors daily for years, roughly 26 to 50 percent higher depending on the study. But that number is smaller than it sounds once it's anchored in real numbers, and every one of these s
Can Kidney Disease Be Reversed? Here's What Really Happens (opens the original)
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Can kidney disease be reversed? A five-year study in PLOS Medicine found that about one in five people with kidney disease saw their numbers return to the normal range. Nephrologist Dr. Sean Hashmi explains what that finding actually means, and why it is different from the "reverse it naturally" promises flooding your feed. You cannot regrow kidney filters that have scarred or died, and chronic kidney disease has no cure. But the two numbers that define kidney health, your filtering score and th
Silent Kidney Stone: Should You Watch It or Treat It? (opens the original)
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Roughly one in twenty CT scans done for something unrelated turns up a silent kidney stone, and "just watch it" is the advice most people hear afterward. Dr. Sean Hashmi, a board-certified nephrologist, walks through what long-term data actually says happens to a silent stone left alone: the risk of a real problem climbs from about 3% at one year to 19% at three years and 31% at five years in a long-term UK cohort, yet close to six in ten stones followed this way for more than five years never n
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