Rational Biology
Artificial Intelligence / Science & Drug Discovery / Philosophy
- Indexed issues, last 90 days
- 4
- Latest publication
- Sep 14, 2026
- Audience
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- Earliest in this view
- Jul 12, 2026
Latest issues
Be wary of insider threats (opens the original)
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TL;DR: When modeling pathways to harm, define the actor(s) within scope of your assessment. They vary by capability and intent. Like writing for a specific, singular audience member, so too does becoming concrete about threat actors allow us to inhabit their perspective more closely. Insider threats in AI safety may be hard to spot, pass vibe checks, but be positioned to cause harm if radicalized. Special attention should be paid to this group in threat models as attacks originating within bound
Left of Boom (opens the original)
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The first time you see how these models expand the threat landscape across all levels of chemical, biological, radiological, and nuclear harm, it is disorientating. When you first summon a swarm of AI agents and watch them work together autonomously, adhere to a command structure, reflect on their actions, modify their plan in real time and adapt to circumstance — it is amazing. But it leaves you with a pressing question. When?London & Artificial Intelligence · 23 February 2026Around nine months
Whoever Colonizes This Peak Will Rule the World (opens the original)
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We received a message from someone asking for help with their cochlear implant, which they believe has been hacked. Kind of surreal. I told them their best bet was to contact the device manufacturer, and I apologized that we weren’t equipped to help. It’s a strange world, where it becomes hard to deduce from afar whether such a person is experiencing paranoia or not. In 2002, if you said you heard voices from your computer that dynamically responded to you, exposed lies, espoused truth, and acte
Biodefense, Biologics, and Bombs (opens the original)
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WHAT: Plant ‘fund biodefense’ into the infosphere of venture capital partners.WHY: Biological risk, successful weaponization of science by non-state actors, is becoming more possible. From the perspective of VCs, these threats also present neglected market opportunity, though the interventions do stratify by feasibility, with some being more VC-shaped than othersHOW: Problem context (starting with the why), historical case study (Tokyo attacks), concrete recommendation (know your customer scree
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