HeyJaredPRISM Rounds: Pulmonary, Critical Care & Sleep Medicine
PRISM Rounds is a Pulmonary, Critical Care & Sleep Medicine podcast that reviews one new article every other week. We break down the study design, statistics, results, and bedside implications—so you can interpret the trial quickly and stay current with the latest research.
- Indexed episodes, last 90 days
- 12
- Latest publication
- Sep 26, 2026
- Audience
- Checking…
- Earliest in this view
- Jul 10, 2026
Latest episodes
S01E59 | ICECAP :Does Longer Cooling Improve Recovery After Cardiac Arrest? (opens the original)
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How long should comatose patients remain at 33°C after out-of-hospital cardiac arrest? In this episode of PRISM Rounds, we examine the icecap randomized clinical trial , which studied 1,158 comatose OHCA survivors who had already been rapidly cooled to 33°C. Patients were assigned to different cooling durations ranging from 6 to 72 hours. Longer cooling did not improve neurological recovery, mortality, or secondary neurological outcomes. We discuss the adaptive trial design, the separate shockab
S01E58: SCCM Heat Stroke Guidelines - Cool Fast, Treat Smart (opens the original)
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In Season 1, Episode 58 of PRISM Rounds , we review the 2025 Society of Critical Care Medicine guideline for the treatment of heat stroke and translate its recommendations into practical bedside decisions for emergency and critical care clinicians. We discuss why active cooling should begin immediately , why cold- or ice-water immersion is preferred when feasible , and why the guideline emphasizes both the speed of cooling and the goal of reaching a core temperature below about 39°C within 30 mi
S01E57 | PRAGUE-26: Early Catheter-Directed Thrombolysis for Intermediate-High-Risk Pulmonary Embolism (opens the original)
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Should we wait for a patient with intermediate-high-risk pulmonary embolism to deteriorate before pursuing reperfusion—or intervene before the right ventricle fails? In this episode of PRISM Rounds , we examine PRAGUE -26 , a multicenter randomized trial published in the New England Journal of Medicine comparing conventional catheter-directed thrombolysis with low-dose alteplase plus anticoagulation against anticoagulation alone in patients with intermediate-high-risk acute pulmonary embolism. T
S01E56 SAVE-O2 AI: Can Oxygen Titrate Itself Better Than We Can? (opens the original)
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In this episode of PRISM Rounds , we discuss the SAVE-O2 AI randomized clinical trial , which tested autonomous closed-loop oxygen titration versus usual manual oxygen adjustment in 300 hospitalized adults receiving supplemental oxygen. The autonomous system kept patients in the target SpO2 range much more often, 85% vs 63% , while also reducing time spent in hypoxemia and, even more strikingly, hyperoxemia. We break down what the trial shows, what it does not show, the importance of pulse oxime
S01E55 | Video Laryngoscopy in the OR: The COVALENT Trial (opens the original)
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Does video laryngoscopy improve first pass success for routine tracheal intubation, and does blade geometry matter? In this episode of PRISM Rounds , we discuss the COVALENT randomized clinical trial, which compared direct laryngoscopy, Macintosh style video laryngoscopy, and hyperangulated video laryngoscopy in more than 2,400 perioperative intubations. We review the higher first pass success with video laryngoscopy, why the hyperangulated strategy performed best, the important role of stylet u
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