HeyJaredPractice Point® CME Podcasts: Expert Discussions in Rare Diseases™
In these podcasts, we dive deep into the world of rare diseases, where every story is unique and every diagnosis a challenge. The episodes highlight the personal journeys of patients and medical professionals as they navigate the complexities of rare conditions.
- Indexed episodes, last 90 days
- 4
- Latest publication
- Jul 23, 2026
- Audience
- Checking…
- Earliest in this view
- Jul 23, 2026
Latest episodes
Episode 37 - Part 4 - Applying the Evidence: A Case-Based Approach to Adult HLH Management (opens the original)
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Using a realistic patient case, this final episode demonstrates how expert clinicians evaluate, diagnose, and manage a patient with suspected adult HLH in real time. Faculty discuss the interpretation of evolving clinical findings, biomarkers, and imaging, while highlighting common diagnostic pitfalls, treatment escalation strategies, and the importance of identifying the underlying trigger. The case illustrates how multidisciplinary decision-making and early intervention can improve outcomes in
Episode 36 - Part 3 - Managing Adult HLH: Trigger-Based Treatment and Emerging Therapeutic Strategies (opens the original)
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Successful management of adult HLH requires simultaneous control of hyperinflammation and identification of the underlying trigger. In this episode, faculty review practical treatment approaches, including corticosteroids, targeted immunomodulatory therapies, and selective use of etoposide-based regimens, while highlighting the growing role of pathway-directed therapies. The discussion emphasizes multidisciplinary care, ongoing reassessment, and individualized treatment decisions based on diseas
Episode 35 - Part 2 - Recognizing Adult HLH Earlier: Clinical Clues and Biomarkers That Matter (opens the original)
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Early recognition is critical to improving outcomes in adult HLH. This episode explores the clinical features, common triggers, and laboratory abnormalities that should raise suspicion for HLH, while reviewing the strengths and limitations of current diagnostic tools, including the HLH-2004 criteria, HScore, and emerging biomarker strategies. Faculty also discuss how trends in ferritin and immune biomarkers can support earlier diagnosis and more informed risk stratification. Launch/Release Date:
Episode 34 - Part 1 - Understanding Adult HLH: Why Early Recognition Matters (opens the original)
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Adult hemophagocytic lymphohistiocytosis (HLH) is a rapidly progressive hyperinflammatory syndrome that often presents with nonspecific features, making early diagnosis challenging. In this introductory episode, expert faculty explain the underlying immunobiology of adult HLH, distinguish primary from secondary disease, and explore why HLH should be viewed as a syndrome rather than a single disease entity. The discussion establishes the clinical framework needed to recognize patients at risk and
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