HeyJaredPharm to Table
A podcast hosted by L.-C. Campeau and Dani Schultz that dives into the stories about the people behind the chemistry and science that happens at MerckChemistry.Follow us on X (formerly Twitter) at @PharmToTablePod, @DrLCSquare, @danithechemistEmail us comments and suggestions…
- Indexed episodes, last 90 days
- 2
- Latest publication
- Aug 11, 2026
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- Earliest in this view
- Jul 15, 2026
Latest episodes
SE5:E3: A Process Chemist's Romance with Scaling a Macrocyclic Peptide (opens the original)
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Last episode, we watched medicinal chemistry dream up enclitide (MK-0616) — this week we find out what happens when someone actually has to make it. Dani and LC are joined by David Thaisrivongs and Gao Shang to unpack their recent JACS paper on the total synthesis of enlicitide, a macrocyclic peptide complex enough to keep company with taxol, vancomycin, and eribulin. Along the way they get into the pivot from solid-phase to solution-phase peptide synthesis, the perpetual headache of sourcing no
SE5:E2: The Macrocyclic Mullet (opens the original)
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What happens when the textbook SAR playbook stops working? On this episode of Pharm to Table , Rob Garbaccio joins Dani and LC to share the discovery story behind enlicitide (MK-0616), a journey filled with unusual SAR, creative problem-solving, and plenty of chemistry twists along the way. From issue-driven drug design to non-canonical amino acids and modular synthesis strategies, this conversation offers a behind-the-scenes look at how real medicines are discovered. If you're training as a che
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