HeyJaredPaired Ends
A practicing data scientist's take on AI, genomics, biosecurity, and the ways AI is reshaping how science gets done. Weekly updates from the field. Occasional notes on programming.
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- Indexed issues, last 90 days
- 14
- Latest publication
- Sep 29, 2026
- Audience
- Checking…
- Earliest in this view
- Aug 10, 2026
Latest issues
September 2026 links (opens the original)
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It’s been a busy month, both in my own life (I landed a new grant! I started teaching!) and elsewhere in my world of science, AI, biology, and academic life. Tomorrow I’m flying down to Mexico City for a week to unplug and recharge. You won’t see much here for a few weeks, but in the meantime, here’s what I’ve been reading this month ¡Nos vemos pronto!Subscribe nowThe AI Discourse in
My relationship with AI is changing (opens the original)
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Personal essay, weekend edition. Starting with a familiar quote often attributed to English economist John Maynard Keynes:1When the facts change, I change my mind. What do you do, sir?I’ve argued here that refusing a useful tool on principle is stubbornness. And after a few weeks of trying to go without AI at all, I still feel that way for the most part
AI + Biosecurity in 4 minutes (opens the original)
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I went on CBS19 TV news here in Charlottesville last night to talk about AI and biosecurity. I thought I was walking into a session that was going to be taped and played over a slow news day. I was pleasantly surprised (and a little thrown off) when I found out the segment was live on the evening news! Here’s the recording. Biosecurity, and AI safety in general, is a really nuanced topic to try to get right in 240 seconds!<a class="image-link image2 is-viewable
Three biological data bills, with OpenAI support (opens the original)
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<img alt="" class="sizing-normal" height="630" src="https://substackcdn.com/image/fetch/$s_!pP50!,w_1456,c_limit,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F0915558e-5ffb-4e52-8352-513c9d7ec745_1200x630.png"
CEPH, CEU, and why Utah reference samples have a French name (opens the original)
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One of the things I love about teaching is that it forces you to confront assumptions and a million little things you don’t fully understand, in case that curious student of yours asks you about it. I’m preparing a lecture for tomorrow morning about various population sequencing projects, from HapMap to 1000 Genomes to ExAC to GnomAD. While preparing to teach the International HapMap Project, I paused for a sec at CEU, a French acronym attached to Utah families from the initial phase of the HapM
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