HeyJaredOsteoSignal with Neal D. O'Neal, PT
Helping you understand the osteopathic model of health so you can move better, adapt better, and truly thrive in life.
- Indexed episodes, last 90 days
- 25
- Latest publication
- Sep 3, 2026
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- Jul 3, 2026
Latest episodes
Your Body Is A Living Forge - OsteoSignal #037 (opens the original)
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Your body never stops building. Every tendon, ligament, and stretch of fascia forms from metals you eat: iron, copper, zinc, magnesium, selenium, manganese. Miss one, and repair stalls, even when standard bloodwork looks fine. This episode breaks down how each metal shapes the tissue therapists feel under their hands, from doughy fascia that won't spring back to muscles that never fully relax. A real patient case shows how iron supplements failed for months until a copper deficiency was found an
The Hidden Cost of Rapid Weight Loss - OsteoSignal #036 (opens the original)
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Millions of people take GLP-1 drugs like Ozempic and Zepbound to lose weight. Here's what nobody tells them: up to 40% of that weight loss is muscle, not fat. This episode breaks down why. These drugs suppress hunger so hard patients can't eat enough protein, and their bodies start cannibalizing muscle and collagen to survive. The result: sagging skin, "Ozempic face," new joint pain, and tissue that feels strange under a therapist's hands. Neal O'Neal, PT, COMT walks through the three lab marker
Your Immune System Has a Nervous System - OsteoSignal #035 (opens the original)
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Your immune cells do more than clean up damage. New research shows macrophages build synapse-like connections with injured muscle fibers, using a protein called PSD95, the same scaffolding protein found at nerve junctions. These cells plug directly into muscle tissue and pump calcium inside, triggering repair. Neal O'Neal and Autumn Mayberry break down what this means in the clinic, including a runner stuck with a hamstring strain for seven months. Her tissue was trapped in a stalled inflammator
Dopamine Isn't the Villain - OsteoSignal #034 (opens the original)
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Your child isn't addicted to their phone. Their brain might be running on empty. This episode flips the dopamine scrolling story on its head. Neal and Autumn argue that doom scrolling doesn't come from too much dopamine. It comes from too little. Dopamine isn't the pleasure chemical. (That’s serotonin.) Instead, it's the switch that lets you stop one task and start another. When a kid or adult can't put the phone down, their brain often lacks the fuel to flip that switch, not because the phone f
The Gut Peptide Quartet - OsteoSignal #033 (opens the original)
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Transcript: https://tinyurl.com/OS033transcript Summary: Your chronic pain patients keep mentioning bloating, reflux, and food sensitivities. That's not a coincidence. This episode of OsteoSignal reveals the biochemical link most manual therapists never learn: your gut runs on four peptides that control far more than digestion. Neal breaks down the "gut peptide quartet": GLP1, GLP2, GIP, and BPC-157. Every time you eat, specialized cells in your intestine release these signals into your bloodstr
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