HeyJaredNucleate Podcast
Nucleate is the new voice for next generation biotech leaders.
- Indexed episodes, last 90 days
- 5
- Latest publication
- Sep 29, 2026
- Audience
- Checking…
- Earliest in this view
- Jul 23, 2026
Latest episodes
Building, Breaking, and Rebuilding Biotech | Deborah Dunsire (opens the original)
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She started out as a small-town GP in South Africa with zero idea a "biotech industry" even existed. Three decades later, Deborah Dunsire had led the launch of Gleevec — the first targeted cancer therapy ever approved — steered Millennium Pharmaceuticals through an $8.8 billion acquisition, and run two more companies through drug failures, board showdowns, and billion-dollar bets. In this episode, she takes us inside the moments that don't make the press release: a phase one cancer patient still
From Nobel-Winning Discovery to Co-Founding Biogen | Phil Sharp (opens the original)
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In this episode of the podcast we are joined by Dr. Phillip Sharp, Nobel Prize Laureate and Institute Professor at MIT, who shares his story behind the groundbreaking discovery of RNA splicing. He explains how the work ethic and problem solving instinctions he built early on eventually led him to Caltech, and then MIT, where his 1977 discovery changed how we understand gene expression. Sharp discusses his journey from science into biotech entrepreneurship, co-founding both Biogen and Alnylam, an
Zero to One: The Precision Medicine Playbook for Cardiac Disease | Nolan Townsend Lexeo Therapeutics (opens the original)
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This episode of the Nucleate Podcast features host Sam Kessler in conversation with Nolan Townsend, CEO of Lexeo Therapeutics, a New York-based clinical-stage biotech developing gene therapies for genetically driven cardiovascular disease. Nolan traces his path from healthcare investment banking at Lehman Brothers into more than a decade at Pfizer, where international P&L roles in Korea, Ukraine, and Western Europe sharpened his ability to navigate ambiguity and different healthcare systems, and
Refusing to give up on an Oncology Breakthrough | Dana T. Aftab, Exelixis (opens the original)
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In this episode of the Nucleate Podcast, Dana Aftab, Executive Vice President, R&D at Exelixis, shares his journey to becoming a leader in drug discovery and what he’s learned along the way. It all began in the homeroom of eighth grade, when a video ignited a passion for biology that would lead him to pursue a Ph.D. in pharmacology at Yale and a defining career in cancer therapeutics. He delves into the different research and drug development projects he’s been a part of, including early breakth
Using Philanthropy to Drive Cures for Multiple Myeloma | Stephanie Oestreich, PhD MMRF (opens the original)
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In this episode, we welcome Stephanie Oestreich, Managing Director at the Multiple Myeloma Research Foundation. She holds a PhD in biochemistry from Harvard Medical School and an MPA from the Harvard Kennedy School, and has worked at the forefront of drug development at major pharma and biotech companies around the world. Stephanie introduces the Multiple Myeloma Research Foundation and delves into the latest advances in in vivo CAR-T and cell therapy that are driving meaningful progress towards
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