HeyJaredNote to File: A Clinical Research Podcast
Note to File is a podcast for clinical research sites - interviews, best practices, and candid commentary from Brad Hightower, founder of Hightower Clinical and clinical research professional.
- Indexed episodes, last 90 days
- 25
- Latest publication
- Aug 11, 2026
- Audience
- Checking…
- Earliest in this view
- Jul 10, 2026
Latest episodes
Wearables, Wagers, and White House Hype (opens the original)
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Note to File gets extra spicy on this one. Brad and Denali riff on everything from wearables and brain health studies to the White House's new "Science: A New Golden Age" report and why U.S. clinical trials are still so painfully slow, expensive, and overburdened. They dig into: - Why consumer wearables like Oura and Whoop still aren't meaningfully integrated into most trials - The gap between "we're in a new golden age of science" headlines and the on-the-ground reality at research sites - The
The Ugly Truth About Site Budgets, IWOs, and "Free" Trial Support with Daniel Fox (opens the original)
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Clinical trial sites are leaking money, often without even realizing it. In this episode of Note to File, Denali and Brad sit down with Dr. Daniel Fox of CRPN (Clinical Research Payment Network) to unpack the ugly truth about site finances, brutal IWOs, "free" trial coaches, and why so many sites end up doing work for zero pay. From unscheduled visits that never get reimbursed to vague CTAs that sponsors happily reinterpret after startup, Daniel breaks down exactly where sites lose money, how to
Anthony Corso on FDA, Trialblazer, and the Policy War Over Clinical Trials (opens the original)
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What happens when DC policy, FDA buzzwords, and real-world site pain all collide? In this episode, Brad and Denali sit down with Anthony Corso, VP of Public Policy at Veeva, to unpack the chaos and opportunity in today's "clinical research renaissance." We dig into: - Real-time clinical trials and the mysterious rise (and fizzle?) of the FDA's Trialblazer initiative - Why "real-time" safety data is mostly a fantasy at the site level - One-and-done Phase 3 trials, master protocols, and how comple
Why Sites Suck at Recruitment (And How To Fix It) (opens the original)
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From National Mac & Cheese Day to the broken economics of centralized recruitment… this Sticky Notes episode goes from nonsense to nuclear takes on how sites really handle patient recruitment. Denali and Brad dig into why so many sites are drowning in bad referrals, buried in tools, and still treating recruitment like a side quest instead of a core competency. They challenge the idea that sponsors and central vendors should own recruitment, and make the case that sites need to embrace what this
Inside the Clinical Research Site Collective: Why Sites Need a Real Advocate with Maria Ladd (opens the original)
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Clinical research sites are *quietly holding all the cards*—so why are they still struggling for support, fair budgets, and real partnership? In this episode of **Note to File**, Brad and Denali sit down with **Maria P. Ladd**, self-declared **Clinical Research Site Advocate** and co-founder of the **Clinical Research Site Collective**, to dig into the gap between sites, CROs, sponsors, and IRBs—and how we can finally start closing it. From **budget negotiations and profit margins** to **IRB rel
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