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Natalie O’Neill

>1 million followers | brutally honest big sister guides on skincare, finance and wellness in your 20s.

Newsletter · By Natalie O’Neill · English · Paid tier available · Official site

Indexed issues, last 90 days
12
Latest publication
Sep 24, 2026
Audience
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Earliest in this view
Jul 9, 2026

Latest issues

  1. Issue · Sep 24, 2026

    11 ultra niche azelaic acid tips for unrecognisable skin (opens the original)

    Excerpt · Neutral tone

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    So many azelaic acid 'experts’ coming out of the woodwork.So few ‘experts’ who’ve used azelaic acid for longer than it’s been trending on social.A lil suspicious to me, but that’s where I can help.I’ve been using Finacea (15% prescription azelaic acid) for three years now, coming up to four.<a class="image-link image2 is-viewable-img" href="https://substackcdn.com/image/fetch/$s_!FECO!,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F

  2. Issue · Sep 16, 2026

    No, PDRN won't fix your fine lines - here’s what actually will. (opens the original)

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    I think you already know this deep down.You just need someone to actually tell you so you can stop wondering if you’re missing out:Yes, PDRN is trending hard on social media right now.It’s doing an amazing job of convincing you it’s something you need.But no, the scientific evidence does not suggest it’s anywhere close to being a miracle for fine lines. Not even close.In this post I’ll cover:What we know about PDRN so far, its strengths and limitationsWhich ingredients are most proven for premat

  3. Issue · Sep 9, 2026

    Why oil cleansers always break you out (+ how to pick ones that don’t) (opens the original)

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    Oil cleansers are one of the most frustrating skincare products to try if you’re acne-prone.Social media raves about how double cleansing can transform other peoples skin - but every time you try an oil cleanser, you have a terrible reaction.And this is for one specific reason - 99% of the popular oil cleansers are made of the same base ingredients.And it’s these ingredients that are the problem.<a class="image-link image2 is-viewable-img" href="https://substackcdn.com/image/fetch/$s_!s9Z8!,f_au

  4. Issue · Sep 3, 2026

    Yes, antibiotics gave you a bumpy forehead (opens the original)

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    When I say I’m an expert in niche skincare issues, I feel like I have lived through dozens of the most niche skin issues you could ever think of.And because they are so niche, a lot of doctors haven’t been able to help me with them.<source type="image/webp"

  5. Issue · Aug 23, 2026

    The ANUA azelaic acid answer we've all been waiting for (opens the original)

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    A month ago I posted my response to SkinEcologic’s viral breakdown of Anua’s azelaic acid.<img class="tiktok thumbnail" src="https://substackcdn.com/image/fetch/$s_!G4Uw!,w_640,c_limit,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F16efd8a4-3d6f-4fbc-b

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