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Discover how modern medicine was built. This podcast explores the careful, often overlooked history of how doctors and scientists identified diseases, uncovered their secrets in the lab, and developed treatments that transformed lives.
- Indexed episodes, last 90 days
- 2
- Latest publication
- Sep 3, 2026
- Audience
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- Earliest in this view
- Jul 27, 2026
Latest episodes
Cholesterol: Xanthomas, Blood, & Bile Linking Cholesterol to Heart Disease (opens the original)
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An eleven-year-old girl, cholesterol-fed rabbits, a wartime centrifuge, and the receptors that transformed our understanding of heart disease. In this episode, we trace how scientists uncovered the connection between cholesterol and atherosclerosis. We begin with an 1889 case involving a young girl covered in xanthomas, then follow cholesterol from its discovery in bile to the fatty plaques found inside diseased arteries. From there, we explore the experiments that showed cholesterol could cause
Asthma: Horses, Fish Scale, IgE - The Story of Elucidating the Mechanism of Allergies (opens the original)
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A blood transfusion, a horse-drawn carriage, fish scales, and a rare cancer that transformed our understanding of allergies. In this episode, Dr. Adam J. Brown concludes the asthma series by telling the remarkable story of IgE—the antibody at the center of allergic disease. We begin with a mysterious 1919 case in which a man seemingly developed a horse allergy after a blood transfusion, then follow the pioneering experiments that revealed allergic sensitivity could be transferred through plasma.
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