MD Longevity Lab: Playing the Long Game with Drs. Vikas and Nisha Patel
🌐 www.mdlongevitylab.com Get in touch.📩 mdlongevitylab.substack.com Follow us on Substack.Hosted by husband-and-wife physicians Dr. Vikas Patel and Dr. Nisha Patel.
- Indexed episodes, last 90 days
- 4
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- Aug 27, 2026
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- Jul 16, 2026
Latest episodes
37. Environmental Curveballs: Sorting Real Toxin Exposure Risk From the Noise (opens the original)
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Wildfire smoke. Cyclospora. Microplastics. Seed oils. Gas stoves. Every environmental scare that'll trend on your feed six weeks from now. Dr. Vikas Patel and Dr. Nisha Patel give you a four-question framework you can apply to any of them — and permission to keep exercising, keep eating vegetables, and stop panic-texting the friend who's out for a run. The core problem: most of us have lost the ability to weigh a risk. Everything gets treated as either "this is fine" or "this is the apocalypse,"
36. Why Dementia Prevention Beats Treatment: APOE Testing, Women's Brain Health, and the Levers You Control (opens the original)
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If you live into your mid-eighties, your odds of dementia are roughly one in three. Most people spend zero minutes of midlife thinking about it — and Dr. Vikas Patel and Dr. Nisha Patel make the case that's backwards, because nearly half of dementia risk traces to things you can actually change. We get into APOE — the gene everyone's testing for and half the time misreading, and what one copy versus two really means. The badly under-told story of women's brain health: two-thirds of Alzheimer's i
35. The Over-40 Injury Playbook: How to Prevent and Rehab Injuries When Life Hands You Lemons (opens the original)
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Anyone over 40 who's felt a tendon go knows the sound — and the sinking feeling right after. Why midlife makes us injury-prone: sedentary weekdays, weekend-warrior spikes, unstructured training, and mechanics that erode while the ambition doesn't. The tissue that pays for it is almost always tendon — Achilles, plantar fascia, rotator cuff, tennis elbow — and tendon doesn't heal like muscle. Which is why "just rest it" is usually the wrong advice for the exact tissue that got you. We cover how to
34. How the Blue Zones Have Mastered Longevity: No Peptides, Just the Basics (opens the original)
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The Blue Zones are the five places on Earth where people routinely live to 100 in good health, without trying — Okinawa, Sardinia, Loma Linda, Nicoya, and Ikaria. They share almost nothing in common except a set of nine habits called the Power 9. And those habits look exactly like the playbook we've been writing all along. Here's the deepest irony of longevity medicine in 2026 — while Americans inject themselves with peptide stacks and pay $40,000 for stem cell tourism, Ikarian grandmothers are
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