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Major Pain

The Major Pain podcast is a collection of interviews from people living with chronic illness and disability. Our goal is to spread awareness, empathy and community around experiences often lived through in isolation.

Podcast · By Jesse Mercury · American English · Official site

Indexed episodes, last 90 days
4
Latest publication
Sep 9, 2026
Audience
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Earliest in this view
Jul 9, 2026

Latest episodes

  1. Episode · Sep 9, 2026

    Relearning Joy After a Lifetime of Medical Trauma with Neuronal Dysplasia (opens the original)

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    When your body is a medical stomping ground, how do you transform it back into a vessel deserving of joy and pleasure? For Melissa—a Seattle-based mental health counsellor—this question arises from a lifelong exploration filled with relapses, flare-ups, malnutrition, and self-discovery. With compassion and confidence, she shares the story of her rare major pain: neuronal dysplasia. At just two days old, Melissa underwent her first surgery. Faced with the news that, if their daughter survived, sh

  2. Episode · Aug 19, 2026

    Love Your Body, Own Your Health: Discussing Type II Diabetes with Kelvin Davis (opens the original)

    Episode notes · Positive tone

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    What does “body positivity” mean to you? To Kelvin Davis, it began as a gap in the market. Women’s clothing advertising was leaning, more and more, into diversity in their models, while menswear seemed content to maintain the status quo of ultra-ripped or ultra-thin. Kelvin launched his body-positive menswear blog, Notoriously Dapper, to address this lack in the fashion industry. Since then, he has published two books and modeled for big names, including Lululemon and Gap. When his Type II Diabe

  3. Episode · Aug 5, 2026

    The Knowledge to Live Better: ALS, Advocacy, and Acceptance with Mindy Uhrlaub (opens the original)

    Episode notes · Neutral tone

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    How do you live with the ever-looming uncertainty of being a gene carrier for a fatal disease? Amyotrophic lateral sclerosis—better known as ALS or Lou Gehrig’s disease—was long believed not to be genetic. Today, however, research shows that 10-15% of cases are linked to the mutation of various genes. The journey of potential future illness is one Mindy Uhrlaub has navigated since 2018, when she learned that she carries the C9OF72 genetic mutation. Since losing her grandfather and then her mothe

  4. Episode · Jul 9, 2026

    ‘Green Plastic Whistle’ Makes Music with Multiple Sclerosis as Disease and Direction (opens the original)

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    Pointing to Edward’s first symptom of Relapse–Remitting MS is tricky. From anxiety in his 20s, to poor sleep and numb hands, to back pain and difficulty walking, the road to diagnosis has been rocky. When he finally received confirmation—in the form of a terrifying MRI showing countless lesions on his brain and spine—Edward was a new father in his early 30s. Coming to terms with a lifelong condition that presents differently for everyone was a process that has slowly shifted his outlook on both

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