Longevity Optimization with Kayla Barnes-Lentz
Maximizing Human Health and Performance. We discuss: optimal health, nutrition, high-performance, cognitive excellence, biohacking, longevity and more with top experts around the world. Hosted by Kayla Barnes-Lentz.
- Indexed episodes, last 90 days
- 8
- Latest publication
- Sep 24, 2026
- Audience
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- Earliest in this view
- Jul 31, 2026
Latest episodes
Carolina Reis Oliveira, PhD: Senescent Cells, Retinol Myths, and the Skin Barrier Body Connection (opens the original)
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Most skincare is designed to improve how aging looks. But can it change what is happening inside the skin itself? In this conversation, I sit down with Carolina Reis Oliveira, PhD, co-founder and CEO of OneSkin, to explore what actually drives skin aging at the cellular level. Carolina explains how senescent “zombie” cells, UV exposure, inflammation, hormonal changes and a weakened skin barrier affect how skin functions, not just how it looks. Get OneSkin's new Rich Cream and the rest of the OS-
Dr. Abud Bakri, MD: Thymus Health, Circadian Biology, and the Truth About Peptides (opens the original)
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Most longevity conversations focus on the brain, heart, muscle, and metabolism. Far less attention goes to the thymus, an immune organ that starts shrinking almost as soon as puberty ends, and new research suggests it may be quietly linked to fertility, hormones, and even how millions of women taking birth control are aging on the inside. I sit down with Dr. Abud Bakri, a board-certified internal medicine physician and hospitalist who founded Systems, a performance and longevity practice built a
Dr. Will Cole: How to Heal Your Cells, Leaky Gut, Light Exposure, and Why Your Gut Sets the Pace To Aging (opens the original)
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We talk about aging like it happens to a whole person at once. It doesn't. It happens organ by organ, at different speeds, and most people never find out which part of them is running ahead until something breaks. Dr. Will Cole has spent sixteen years running one of the first functional medicine telehealth centers in the world, and he came to this conversation with a case that is both clinical and personal. In 2023 his father lost consciousness at the wheel and died in the crash. The autopsy poi
Dr. Tania Dempsey, MD: Mast Cell Activation Syndrome, PMOS, and the Hidden Cause of Women's Chronic Symptoms (opens the original)
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Most women who deal with unexplained allergies, stubborn inflammation, heavy periods or a PMOS (formerly PCOS) diagnosis are never told to look at the same underlying cause: an immune cell most doctors were never taught to test for. Dr. Tania Dempsey, MD, trained in internal medicine at Johns Hopkins before leaving conventional practice to focus on mast cell activation syndrome, a condition she believes explains far more chronic illness in women than most doctors realize. She's the founder of Th
Dr. Margie Davenport, PhD: Exercise in Pregnancy, the 140 BPM Myth, and Why Pregnancy Complications Predict Heart Disease (opens the original)
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Pregnancy has long been treated as a season to slow down and play it safe. The data tells a different story, and it starts with a number most women were taught to fear. Dr. Margie Davenport, PhD, is an exercise physiologist and professor at the University of Alberta who has spent over a decade studying how the body moves through pregnancy, postpartum, and the years before. What stayed with me most: a pregnancy complication isn't just a pregnancy problem. It's information about a woman's future h
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