HeyJaredLipedemaScience
LipedemaScience follows the evolving research on lipedema, critically examines what the evidence does and does not show, and translates it into useful knowledge for people living with the condition.
- Indexed issues, last 90 days
- 11
- Latest publication
- Sep 30, 2026
- Audience
- Checking…
- Earliest in this view
- Sep 19, 2026
Latest issues
Hunger and Fullness Hormones: GLP-1, Ghrelin, Leptin and Appetite in Lipedema (opens the original)
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Why can one person finish a meal and feel satisfied for hours, while another becomes hungry again quickly or continues wanting food despite having eaten enough? Hunger and fullness are regulated through communication between the gastrointestinal tract, adipose tissue, pancreas, brain and reproductive system. Hormones including ghrelin, GLP-1, PYY, CCK, leptin and insulin participate in this regulation, while reproductive hormones and the physiological stress response can modify appetite further.
Why Your Lipedema Triggers May Change Over Time (opens the original)
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One of the most important things I have learned from living with lipedema for almost 15 years is that my triggers are not always my triggers.That probably sounds contradictory. Refined sugar, for example, is something I identified as a personal trigger very early, around the time I was diagnosed in 2012. I noticed that there were occasions when eating a lot of refined sugar seemed to be followed by more pain and sensitivity in my tissue. I did not learn this from a lipedema community, because I
Lipedema Research News: What Changed in September 2026 (opens the original)
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It has been an unusually busy month in lipedema research. Since September 2, a major trial has reported on liposuction and pain, while new studies have explored diet, tirzepatide, gestrinone, shock-wave therapy and the way lipedema pain is measured. There has even been a proposal to change the name of the condition.Get 50% off for 1 year<a class="image-link image2 is-viewable-img" href="https://substackcdn.com/image/fetch/$s_!NK
Why I Would Never Give Up Fiber (opens the original)
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There are many reasons I would never go fully carnivore as a food scientist living with lipedema.<img alt="Why everyone is talking about the carnivore diet - myDr.com.au" class="sizing-normal" height="900" src="https://substackcdn.com/image/fetch/$s_!mxLC!,w_1456,c_
The Nervous System Has an Impact on Your Lipedema Inflammation (opens the original)
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I was diagnosed with lipedema in 2012, when I was 20 years old. In many ways, I was lucky to get the diagnosis that early. We know that many women spend years trying to understand why their legs hurt, why they bruise so easily, or why their body seems to change differently from the people around them. I had a diagnosis relatively early, but I did not have much information about what to do with it.“The vagus nerve is not the only connection between psychological state and immune function.”The lip
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