HeyJaredJames H. Stein, MD
I’m a preventive cardiologist and professor with over 36 years caring for patients and researching cardiovascular disease. I aim to make health and science clearer and more approachable. Not monetized. My views, not medical advice.
- Indexed issues, last 90 days
- 15
- Latest publication
- Sep 27, 2026
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- Jul 19, 2026
Latest issues
“Your Doctor is an Idiot” (opens the original)
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This is the first of two pieces about internet physicians whose content undermines patients' trust in their own doctors. This post looks at those who imply that your doctor is an idiot for not ordering a test or prescribing a drug. The next piece looks at how critical appraisal, the core discipline of evidence-based medicine, can curdle into reflexive cynicism.<a class="image-link image2 is-viewable-img" href="https://substackcdn.com/image/fetch/$s_!TxEl!,f_auto,q_auto:good,fl_progressive:steep/
Variability in Lp(a) Measurements: A Brief Primer (opens the original)
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This post is a bit of “inside baseball,” or “inside lipidology,” but so many people are having Lp(a) levels measured, and we are asked about repeat values so often, I thought this primer might be useful to you and your patients.<source type="image/w
Curious Cholesterol Cases from Clinic, #5: When Triglycerides Don’t Match the Body Habitus (opens the original)
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“Curious Cholesterol Cases from Clinic” is a series built around real-world lipid cases, some of which look obvious at first glance but turn out not to be what they seem. They are presented as clinical unknowns for teaching purposes and are relevant to primary care, cardiology, and related subspecialties. Identifiers have been removed or altered and certain details modified to protect privacy and comply with HIPAA. These cases are real and presented solely for educational purposes.A 65-year-old
There’s No Crying in Cardiology! (opens the original)
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<img alt="" class="sizing-normal" height="819" src="https://substackcdn.com/image/fetch/$s_!e1ty!,w_1456,c_limit,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F7dc2aa10-b310-4fb6-b90d-ca7d70108bbf_1536x864.jpe
The Bias We Call Expertise: How It Shapes Clinical Practice Guidelines (opens the original)
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Note: My career mentor and dear friend, Norman Fost, MD, MPH, contributed to this essay and helped refine its arguments.Financial conflicts of interest receive enormous attention in medicine because they can influence interpretation of evidence, framing of recommendations, and patient care. We ask guideline and manuscript authors to disclose financial relationships because we recognize that incentives can shape judgment, yet disclosure is an imperfect remedy, since secrecy is not the primary pro
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