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From First Principles

From First Principles is a fast, funny, and rigorous breakdown of the biggest science stories of the week, hosted by Lester Nare and physicist Krishna Choudhary, PhD.

Podcast · By Krishna Choudhary and Lester Nare · American English · Official site

Indexed episodes, last 90 days
12
Latest publication
Sep 24, 2026
Audience
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Earliest in this view
Jul 3, 2026

Latest episodes

  1. Episode · Sep 24, 2026

    What OpenAI Actually Did to Navier-Stokes (EP 58) (opens the original)

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    What does it mean to solve an equation that describes almost every fluid around us, from the air over a wing to the water swirling down a drain? In Episode 58 of From First Principles, Lester Nare and Krishna Choudhary build the Navier-Stokes equations from the ground up before digging into OpenAI’s claimed breakthrough and the debate surrounding it. Summary How Newton’s laws become equations for a moving fluid Velocity fields, incompressibility, pressure and the nonlinear convective term Why vi

  2. Episode · Sep 14, 2026

    What’s Next in Science? Nobel Prizes, Space Missions & More (EP 57) (opens the original)

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    What science should you be watching this fall? From Nobel Prize season to NASA’s Roman Space Telescope, Mars’ moons and Mercury, Lester Nare and Krishna Choudhary take a relaxed tour of the discoveries and missions on their radar. In Episode 57 of From First Principles, we explore why curiosity-driven research matters, what the Golden Goose Awards celebrate, and how questions that once sounded impractical can lead to unexpected breakthroughs. Then we turn to space: Roman’s search for dark energy

  3. Episode · Sep 7, 2026

    The Yak Mutation That Could Help Repair the Brain (EP 56) (opens the original)

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    What can a yak living thousands of meters above sea level teach us about repairing the human brain? In Episode 56 of From First Principles , Lester Nare and Krishna Choudhary break down a new Neuron paper that traces an evolutionary adaptation found in high-altitude animals to a previously hidden pathway involved in building and repairing myelin. Summary What myelin actually does and why losing it disrupts neural communication How multiple sclerosis damages myelin and why the brain’s natural rep

  4. Episode · Aug 31, 2026

    Why Spin Qubits Will Win the Quantum Race (Part 2) (EP 55) (opens the original)

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    Which quantum computer will actually scale? In Part 2 of our quantum computing deep dive, Lester Nare and Krishna Choudhary move from theory to hardware—comparing superconducting qubits, trapped ions, neutral atoms, and silicon spin qubits before going inside the new Nature cover paper Krishna co-authored with the HRL Quantum Team and collaborators. The episode begins with a simple question: what makes a good quantum computer? We evaluate each architecture using three criteria: qubit quality, qu

  5. Episode · Aug 20, 2026

    How Quantum Computing Actually Works (Part 1) (EP 54) (opens the original)

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    Quantum computers do not simply “try every answer at once.” So what do they actually do—and why have governments and technology companies spent billions trying to build them? In Part 1 of our two-part quantum computing deep dive, Lester Nare and Krishna Choudhary build the field from first principles. The series was prompted by a new Nature cover paper, A digitally controlled silicon quantum processing unit , co-authored by Krishna and members of the HRL Quantum Team and collaborators. Before ge

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