HeyJaredFightAging!
FightAging! is a specialized science-focused publication dedicated to aging research, rejuvenation biotechnology, and life extension.
- Indexed articles, last 90 days
- 17
- Latest publication
- Aug 3, 2026
- Audience
- Top 5M sites
- Earliest in this view
- Jul 3, 2026
Latest articles
Reviewing the Present State of Development of Senomorphic Therapies (opens the original)
Read excerpt
Senescent cells accumulate with age and contribute to degenerative aging via their pro-growth, pro-inflammatory signaling. Even when less than 1% of all cells are senescent in a tissue, the signaling generated by those senescent cells alters the behavior of other cells for the worse, and is disruptive to tissue structure and function. When it comes to what to do about the burden of senescent cells in aged tissues, much of the focus is on the development of senolytic drugs that can selectively de
Differences by Sex Observed in BCL-2/BCL-xL Senolytic Treatment for Intervertebral Disc Degeneration (opens the original)
Read excerpt
A number of prevalent age-related conditions are notably different in timing and progression between the sexes. No doubt the list of differences by sex will grow as the research community explores the first therapies that target important mechanisms of aging. Here, researchers report on an attempt to treat intervertebral disc degeneration in mice using a senolytic drug that selectively destroys the BCL-2 and BCL-xL proteins that a senescent cell needs in order to resist programmed cell death. Th
The Cribriform Plate Path for Cerebrospinal Fluid Drainage Also Has a Glymphatic System (opens the original)
Read excerpt
Cerebrospinal fluid drainage from the brain into the body is necessary to remove metabolic waste from the brain. The flow declines with age, and evidence strongly suggests that this is an important contribution to the build up of protein aggregates and other waste that drive the onset and development of neurodegenerative conditions. Much of the focus is on the glymphatic system of vessels at the base of the brain, but because Alzheimer's disease starts in the olfactory bulb region of the brain,
Fight Aging! Newsletter, August 3rd 2026 (opens the original)
Read excerpt
Fight Aging! publishes news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine. This weekly newsletter is sent to thousands of interested subscribers. To subscribe to the newsletter, please visit: https://www.fightaging.org/newsletter/. To unsubscribe, send email or reply to this email at newsletter@fightaging.org with "unsubscribe" in the subject or body. Longevity Industry Consulting Ser
Restoring Clearance of Neutrophils by Tissue Resident Macrophages Reverses Measures of Aging in Mice (opens the original)
Read excerpt
Senescent cells accumulate with age in tissues throughout the body. These cells cease replication and secrete a potent mix of pro-growth, pro-inflammatory signaling that is disruptive to tissue structure and function when maintained over the long term. Cells become senescent throughout life in response to various circumstances, but in youth are efficiently destroyed by the immune system. With old age, the immune system falters in this task for reasons that are still being explored in detail. Whi
Publishing over time
Last 90 days. Choose a month to open its work.
Recurring subjects
Named in the text we hold. One piece can cover several.
Audience
Top 5M sites
Measured Aug 1, 2026
Website popularity band, not a count of readers or article views.
About this data
Counts cover the work we have indexed. Tone needs enough text and a confident classification. Excerpts and episode notes are not full articles or transcripts.
Identity or attribution wrong? Suggest a correction.