Don't Just Read the Abstract

1. Episode · Sep 8, 2026

   HI-PEITHO: Does catheter-directed fibrinolysis improve outcomes in intermediate-risk PE? (opens the original)

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   On this episode, Pip and Rich discuss HI-PEITHO , a randomised controlled trial of catheter-directed fibrinolysis in patients presenting with intermediate risk PE. This was an industry-sponsored trial. Patients could be included if they had a ratio of RV:LV end diastolic diameter of ≥1.0 and an elevated troponin level + at least two of SBP ≤110 mm Hg, HR ≥100 bpm, or a respiratory rate of >20 breaths per minute. The primary outcome was a composite of pulmonary embolism–related death, cardiorespi

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2. Episode · Aug 2, 2026

   C-TRACT: does venous stenting make a difference in post-thrombotic syndrome? (opens the original)

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   In this episode, Pip and Rich discuss the C-TRACT trial: Vedantham et al. Endovascular Therapy for Post-Thrombotic Syndrome — A Randomized Trial. 2026 N Engl J Med 2026;394:2293-2304 C-TRACT (Chronic Venous Thrombosis: Relief with Adjunctive Catheter-Directed Therapy) was a phase 3, publicly funded, multicentre, open-label, assessor-blinded RCT published in NEJM that randomised 225 patients with moderate-to-severe post-thrombotic syndrome (PTS) and imaging-confirmed iliac-vein obstruction to end

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• Pip and Rich2 pieces
• Novo Nordisk1 piece
• CI1 piece
• Hosted on Acast1 piece
• the Venous Clinical Severity Score1 piece
• QOL1 piece
• PTS1 piece
• VEINES-QOL1 piece
• HaemSTAR1 piece
• Key Results1 piece
• Vedantham1 piece
• RCT1 piece

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