HeyJaredCreative Destruction
Harnessing the forces of Creative Destruction. How business, finance, and technology industries drive prosperity and improve the human condition.
- Indexed issues, last 90 days
- 10
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- Sep 10, 2026
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- Earliest in this view
- Jul 7, 2026
Latest issues
Two Years in Six Weeks (opens the original)
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<img alt="" class="sizing-normal" height="971" src="https://substackcdn.com/image/fetch/$s_!dn4c!,w_1456,c_limit,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F8d3794ee-24ee-4a1f-a209-f5e215574716_1536x1024.pn
Twelve Meters - Chapter Two: Not Yet (opens the original)
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This is a work of fiction.Real institutions, agencies, locations and a small number of public figures appear as settings and reference points. Everything else is invented: the two agents, the technician, the officers on both sides, the travelers, the collection programs, and every deliberation depicted in Beijing and in Washington. No real person is depicted as having done, known, or concealed anything.Do read Chapter 1 FirstC
Twelve Meters - Chapter One: By Procedure (opens the original)
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This is a work of fiction.Real institutions, agencies, locations and a small number of public figures appear as settings and reference points. Everything else is invented: the two agents, the technician, the officers on both sides, the travelers, the collection programs, and every deliberation depicted in Beijing and in Washington. No real person is depicted as having done, known, or concealed anything.Chapter One: By ProcedureWuhan Institute of Virology, Xiaohongshan campus. 29 July 2019, 1840
Prevention Is the Only Real Price Control in Healthcare (opens the original)
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The conventional claim that U.S. healthcare spending is a dramatic outlier, and therefore proof that single-payer is required, is overstated. Higher healthcare consumption in the US underwrites the creative destruction that improves per-incidence outcomes globally. Healthcare costs are untenable in total, because a failure to prevent chronic disease is a free rider on Medicare and Medicaid.When national health expenditure is measured against Actual Individual Consumption (AIC) rather than GDP pe
Where the Blood Goes (opens the original)
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Two drugs earned $71 billion in 2025. Semaglutide and tirzepatide. More than double OpenAI and Anthropic combined. Tirzepatide is now the best-selling pharmaceutical on earth, and both did it, reaching under 2% of the people who qualify.<img alt="" class="sizing-nor
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