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Core Memory

Core Memory is a podcast about science and technology hosted by best-selling author and filmmaker Ashlee Vance. Vance has spent the past two decades chronicling advances in science and tech for publications like The Economist, The New York Times and Bloomberg Businessweek.

Podcast · By Ashlee Vance · English · US · Official site

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Indexed episodes, last 90 days
8
Latest publication
Sep 9, 2026
Audience
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Earliest in this view
Jul 8, 2026

Latest episodes

  1. Episode · Sep 9, 2026

    The Xbox Nearly Destroyed Him - EP 87 Seamus Blackley (opens the original)

    Episode notes · Neutral tone

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    This episode is nerd catnip unlike anything I’ve ever seen before. Ashlee sat down with Seamus Blackley, who you might know as the man who talked Microsoft into building the Xbox. Nowadays, you can find Blackley in a Pasadena laboratory making the world’s best chocolate. If you’re just here for the cacao, well, we did a video on it . Blackley grew up in rural New Mexico and studied electrical engineering, then physics, at Tufts University. He spent years working on titles you know and love, like

  2. Episode · Sep 2, 2026

    Gene Therapies That Work? - EP 86 Adrian Veres (opens the original)

    Episode notes · Positive tone

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    We have been promised glorious gene therapies for decades. This is supposed to be the stuff of reprogramming the body to blunt or cure diseases with something approaching a permanent fix. While gene therapy progress has been made, treatments remain rare and expensive, and it’s very tough to get the therapies to go into the desired parts of the body. Our guest this week is here to help. He’s Adrian Veres, the chief scientific officer and co-founder of Dyno Therapeutics . Founded in 2018, Dyno has

  3. Episode · Aug 26, 2026

    The Realest Longevity Guru - EP 85 Alex Colville (opens the original)

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    Over the past five years, Alex Colville has become one of the most influential figures in the longevity and aging fields. There’s a decent chance you have not heard of him, which is a bit by design. Unlike many longevity gurus, Colville does not seek much attention and, for the most part, operates in the background where he’s been doling out many millions of dollars in investments. Today, Colville runs age1 , a venture capital firm that has backed the likes of Loyal, Science, Conception and a bu

  4. Episode · Aug 20, 2026

    AI Will Cure Us All!! Or Not!! - EP 84 Abhi Mahajan (opens the original)

    Episode notes · Positive tone

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    Every couple of days, a new AI-meets-biotech startup sends me a pitch, and the pitches all sound the same. AI is amazing, and it can now tame biology. We’re on the cusp of producing new cures for diseases at a rapid rate, and these startups know just how to get the job done. To which you should wonder – is this at all true? On this week’s Core Memory episode, we have brought in the big brains to answer – or at least debate – this question. Our resident science whiz and medical professional Eryne

  5. Episode · Jul 22, 2026

    The Google Engineer Who Set The Skydiving Record At 58 - EP 83 Alan Eustace (opens the original)

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    Most people think that the Red Bull guy Felix Baumgartner holds the skydiving record. But this is not the case. The real record-holder is Alan Eustace. In 2014, at age 58, the Google engineer rode a helium-filled balloon into the stratosphere and then fell back to Earth from 135,890 feet. Eustace’s fall lasted 4 minutes and 27 seconds, and he broke the sound barrier, reaching a max speed of 822 mph. And now, in a very rare appearance, Eustace has come on the podcast to discuss his adventure. Bau

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