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ASeq Newsletter

ASeq is Nava Whiteford’s newsletter on DNA sequencing, protein sequencing, diagnostics, life-science tools, biotech company strategy, COGS. And all sorts of other biotech related fun!

Newsletter · By Nava Whiteford · Official site

Indexed issues, last 90 days
11
Latest publication
Sep 30, 2026
Audience
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Earliest in this view
Aug 25, 2026

Latest issues

  1. Issue · Sep 30, 2026

    On Protein Sequencing (opens the original)

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    We’ve going to talk about protein sequencing again! A few more bits an pieces have emerged and I remain cautiously excited about one company in particular.So...PumpkinSeed have a preprint out.Portal and Oxford Nanopore had posters at HUPO (posted on the Discord)1.So, let’s take a look! Read more </

  2. Issue · Sep 23, 2026

    AI First Analysis For Startups (opens the original)

    Excerpt · Neutral tone

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    I’ve been thinking a lot about AI recently. I’ve mostly been an AI skeptic.I still don’t like DNA sequencers with AI in the basic workflow1. And I’m less than positive about basecalling workflows that require significant inference2.But I’m getting much more bullish about the ability of AI to build analysis pipelines.Models seem to have got a lot better in the last 6 months. Yesterday

  3. Issue · Sep 22, 2026

    ChatGPT Basecall PacBio Movie, No Mistakes (opens the original)

    Excerpt · Positive tone

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    I’ve been using Claude and ChatGPT for a few exploratory data analysis projects recently. They’ve very good… scary good. Probably better than me in most cases.There are times it screws up. And I do feel like I’m helping, but then again maybe that’s just what Claude wants me to think.A project I’ve always wanted to work on is trying to do some analysis of the only PacBio raw data which is publicly available. It comes from this paper. And the data isn’t really sequence data. It’s just C and G even

  4. Issue · Sep 16, 2026

    MGI Nanopore EU Injunction (opens the original)

    Excerpt · Critical tone

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    Genomeweb is reporting an injunction against the MGI, stopping them from selling nanopore sequencers in Europe.Oxford Nanopore made some statements1, MGI made some statements2 and it seems a full trial will proceed in <a href="https://otp.tools.investis.com/clients/uk/oxford

  5. Issue · Sep 14, 2026

    PacBio Alternative Apps (opens the original)

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    PacBio have never really gone after “alternative applications” on their platform, not to the degree that Oxford Nanopore have.In some ways this is understandable.I don’t think direct RNA sequencing, for example, has generated significant revenue for Oxford. But it’s a shame that direct RNA sequencing was demonstrated on PacBio’s platform in 2009, but just never released<a class="footnote-anchor" href="#footnote-1

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