AI for Founders with Ryan Estes
AI for Founders is where 47,000+ founders learn to build and scale with AI. Hosted by Ryan Estes, a Denver investor, creator, and founder, the show breaks down real strategies from top operators and AI visionaries.
- Indexed episodes, last 90 days
- 30
- Latest publication
- Sep 11, 2026
- Audience
- Checking…
- Earliest in this view
- Jul 6, 2026
Latest episodes
15 beagles, 4 cancers, 94% accuracy: my favorite AI workflow in health tech (opens the original)
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Thirteen days from now, the FDA convenes a panel that has never convened before. On September 23, 2026, the Molecular and Clinical Genetics Panel sits down to vote on Grail's Galleri test, the first multi-cancer early detection test ever to reach an FDA advisory committee. Every founder building in early detection is watching. Shlomi Madar is watching too. He just is not building the same thing. Madar is the CEO of SpotitEarly, an Englewood, New Jersey company founded in 2020 that screens for fo
How to automate a board of advisors for $29 a month (opens the original)
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Nobody warns you that traction is the lonely part. Broke and scared has company. Everybody has been broke and scared. What nobody prepares you for is the 11 PM decision, three years in, revenue real, team growing, and not a single person left who understands the shape of the problem. Your friends stopped relating around round two. Your family cannot parse the question. Your team needs you to already know. Steve Phillips solved that problem the hard way, six times. He is the founder of Zappi, the
Why your AI-designed brand is invisible, and the 3-step fix (opens the original)
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Everyone got the same tools. Almost nobody got taste. Jacqueline Schmidt grew up two subway stops from tigers. The Bronx Zoo was her backyard. Her favorite exhibit was the sloth, which she went back to visit twenty-five years later and found out had died. She spent summers collecting salamanders in the woods and carrying them home in her Smurf boots, fifty at a time, to the ongoing horror of her grandparents. She drew animals constantly. Then she sold the drawings. Then the drawings became a com
The 10-minute morning routine that replaced an entire project management stack (opens the original)
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Five days. Twelve-hour build sessions. One founder describing himself as delirious. Jason Katz opens this one by announcing he has AI psychosis, and he is only half joking. Five straight days inside Claude Code, shipping, prototyping, handing off to his dev team, and coming back for more. It is the kind of week that either produces a business or produces a burnout, and the whole episode is really about the difference between those two outcomes. Ryan is in the same trench from the opposite direct
8.3 billion faces, zero infrastructure: the AI likeness market nobody is serving (opens the original)
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Sixty percent of the faces training AI were never asked Katrien Grobler woke up on the 29th of December and saw a word written above her bed. Not metaphorically. She describes seeing the name in her mind's eye, getting up, and telling her team they were pivoting that day. The word was Twinnin. She had spent the previous year running AI KAT, making AI-generated video ads for clients like Capital.com and Reckitt's Dettol brand. On one project she needed a trader character. Rather than generate a s
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